Take fexofenadine (Allegra) 180mg daily

What to Do

Take one fexofenadine 180mg tablet daily. It is truly non-sedating — the only OTC antihistamine with zero measurable drowsiness at any dose.

Why It Works

Fexofenadine does not cross the blood-brain barrier at all, making it the safest choice for people who drive, operate machinery, or need full mental sharpness. Onset is 1-3 hours with 24-hour duration.

Tips

• Do not take with fruit juice (orange, apple, grapefruit) — it reduces absorption by up to 36%
• Take with water on an empty stomach for best results
• Slightly less potent than cetirizine for severe symptoms
• Available as 60mg twice daily for children ages 2-11