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Best Japanese knotweed (resveratrol) supplements for Lyme protocols?

Comparing Japanese knotweed (Polygonum cuspidatum) supplements. The protocol calls for 500 mg whole-herb capsules. Knotweed contains resveratrol and emodin, both shown to have activity against Borrelia persisters in laboratory studies.

📅 Created: 3/4/2026, 5:20:45 AM
Rating ▼BrandCost/ServingProtocol MatchResveratrolForm
5.0 (1)Supreme Nutrition Japanese Knotweed SupremeUSD 0.60
Exact
Whole herb, protocol-recommended brand
Not standardized (whole herb)Veggie capsule 375mg
3.0 (1)Double Wood Supplements Resveratrol 500mgUSD 0.33
Partial
Standardized extract, not whole herb
50% (250mg trans-resveratrol)Veggie capsule 250mg
3.0 (1)Nutricost Resveratrol 700mgUSD 0.52
Partial
Standardized extract, not whole herb
50% (350mg trans-resveratrol)Veggie capsule 350mg
3.0 (1)NOW Foods Extra Strength Resveratrol 350mgUSD 0.36
Partial
Standardized extract, not whole herb
50% (350mg trans-resveratrol)Veg capsule 700mg extract
3.0 (1)Source Naturals Resveratrol 200USD 0.22
Partial
Standardized extract, lower dose
50% (200mg trans-resveratrol)Vegetarian capsule 200mg

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