Ask about prescription alcaftadine drops (Lastacaft) for severe eyes

What to Do

Ask your allergist or ophthalmologist about alcaftadine 0.25% (Lastacaft) prescription eye drops if OTC options are not providing adequate relief. Use 1 drop per eye once daily.

Why It Works

Alcaftadine uniquely blocks H1, H2, and H4 histamine receptors — broader coverage than OTC drops that only block H1. It also stabilizes mast cells and inhibits eosinophil infiltration. Clinical trials show superior itch prevention compared to olopatadine in some head-to-head studies.

Tips

• Once-daily dosing for convenience
• Can be used while wearing contact lenses (unlike most allergy drops)
• Prescription cost varies; check manufacturer coupons
• Reserve for cases where OTC ketotifen or olopatadine are insufficient